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Life after death for the human eye

Scientists have revived light-sensing neuron cells in organ donor eyes and restored communication between them as part of a series of discoveries that stand to transform brain and vision research. … Source link

Retinal cell map could advance precise therapies for blinding diseases

Researchers have identified distinct differences among the cells comprising a tissue in the retina that is vital to human visual perception. The scientists from the National Eye Institute (NEI)… Source link

NEI researchers discover cellular events that precede neurodegenerative eye disease

Molecular and cellular changes in rod photoreceptors are detectable in a mouse model of retinal degeneration several days prior to observable morphological changes, according to researchers at the… Source link

Ophthalmologists are Making a Difference in the Fight Against Climate Change

In 2018, an 82-year-old woman experienced mild pain after eye surgery, so her ophthalmologist applied some ointment to ease her discomfort. Instead of throwing away the tube of medication as hospital policy required,… Source link

Vision improvement is long-lasting with treatment for blinding blood vessel condition

New research shows that a treatment for retinal vein occlusion yields long-lasting vision gains, with visual acuity remaining significantly above baseline at five years. However, many patients… Source link

How Do Our Eyes Stay Focused on What We Reach For? Researchers Uncover How Our Gaze is “Anchored” in the Brain

Keeping our eyes focused on what we reach for, whether it be an item at the grocery store or a ground ball on the baseball field, may appear seamless, but, in fact, is due to a complex neurological… Source link

Scientists unveil the format of working memory

A team of scientists has discovered how working memory is “formatted”—a finding that enhances our understanding of how visual memories are stored. “For decades researchers have wondered… Source link

Ultrasound Gave Us Our First Baby Pictures. Can It Also Help the Blind See?

Research funded by the National Eye Institute and led by a team at the University of Southern California Viterbi School of Engineering’s Department of Biomedical Engineering is exploring a… Source link

New UCI-led study lays foundation for establishing base editing as a one-time, durable treatment for inherited retinal degeneration

A new University of California, Irvine-led study indicates base editing may provide long-lasting retinal protection and prevent vision deterioration in patients with inherited retinal degeneration,… Source link

Scientists pinpoint what makes brain cells develop in a specific order

Researchers have identified the complete series of 10 factors that regulate the development of brain cell types in the visual system of fruit flies—including in what order these neurons develop…. Source link

Decoding the molecular clock that controls neurogenesis in the visual center of Drosophila

The nervous system is made up of diverse cells that arise from progenitors in a specific time-dependent pattern. In a new study, published in Nature Communications, researchers have uncovered the… Source link

Correcting night blindness in dogs

University of Pennsylvania researchers have developed a gene therapy that restores dim-light vision in dogs with a congenital form of night blindness, offering hope for treating a similar condition… Source link

Links Blueprint Neurotherapeutics Network (BPN) for Small Molecules

NIH Program offers path from basic science to clinical testing and regulatory approval The road from discovering a potential drug to getting… Source link

How Eye Imaging Technology Could Help Robots and Cars See Better

Even though robots don’t have eyes with retinas, the key to helping them see and interact with the world more naturally and safely may rest in optical coherence tomography (OCT) machines commonly… Source link

Antabuse may help revive vision in people with progressive blinding disorders

Researchers at the University of California, Berkeley, have found that a drug once widely used to wean alcoholics off of drinking helps to improve sight in mice with retinal degeneration. The drug… Source link

Attention to objects in peripheral vision is not driven by tiny eye movements

Minuscule involuntary eye movements, known as microsaccades, can occur even while one is carefully staring at a fixed point in space. When paying attention to something in the peripheral vision… Source link

Seen and ‘herd’: Collective motion in crowds is largely determined by participants’ field of vision

Like flocks of birds or schools of fish, crowds of humans also tend to move en masse — almost as if they’re thinking as one. Scientists have proposed different theories to explain this type of… Source link

NEI hosts international strategic planning meeting

The digital summit of global partners in vision research discussed opportunities for collaboration. “We’re here because we all want the same thing: a… Source link

Indiana University-led study shows human induced pluripotent stem cells improve visual acuity, vascular health

Researchers at Indiana University School of Medicine, in collaboration with the University of Alabama at Birmingham and five other institutions, are investigating novel regenerative medicine… Source link

The Delay is the Point: An Ophthalmologist Navigates Abusive Health Insurer. Barely

I’ve often done battle with insurance companies to get my patients the health care they need. I’ve also been the patient at the end of the phoneline – for hours – with no idea if help is on the way. Health… Source link

Bunkers that save sight? UConn researchers take a close look

Healthy aged human retinas (J,K,L) have minimal stress proteins (green, J), little citrullination (red, K) and very little overlap (L), indicating low stress levels. In contrast, human retinas with… Source link

Protein protects brain cells most impacted by glaucoma

Kathryn Bollinger and Sylvia Smith, Augusta University, reported that protein sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of retinal… Source link

Vision scientists discover new angle on path of light through photoreceptors

Researchers at the National Eye Institute (NEI) have discovered that power-producing organelles in the eye’s photoreceptor cells, called mitochondria, function as microlenses that help channel… Source link

Mosquitoes are seeing red: Why new findings about their vision could help you hide from these disease vectors

Beating the bite of mosquitoes this spring and summer could hinge on your attire and your skin. New research led by scientists at the University of Washington indicates that a common mosquito species… Source link

Implanted chip, natural eyesight coordinate vision in study of macular degeneration patients

Two years ago, a Stanford researcher and his team showed that with a thin, pixelated chip and specially designed glasses, they could restore limited vision in the center of the visual field of… Source link

Report on anterior segment inflammation and immunity posted

NEI has published an executive summary from the April 23, 2021, virtual workshop “Immunity and Inflammation in the Anterior Segment of the Eye,” hosted by the NEI Anterior Segment Initiative. … Source link

Digital Strain Infographic

UW study finds photoreceptor cells from retinal organoids can replicate key function of vision

Researchers from the University of Wisconsin (UW) have shown that cone photoreceptors from retinal organoids – lab-produced versions of light-sensitive eye tissue – are similar to cones in a… Source link

Maintaining Transparency: Study to Focus on Causes of Cataracts

Cataracts affect more than 15 million people worldwide and are the leading cause of blindness, especially in regions with a lack of access to qualified surgeons. Researchers at the University of… Source link

AI can identify heart disease from an eye scan

Scientists have developed an artificial intelligence (AI) system that can analyze eye scans taken during a routine visit to an optician or eye clinic and identify patients at a high risk of a heart… Source link

UCI researchers discover cause, develop pharmacological treatment for reducing retinitis pigmentosa vision loss

Researchers from the University of California, Irvine have discovered that the absence of Adiponectin receptor 1 protein (AdipoR1), one of the principal enzymes regulating ceramide homeostasis in the… Source link

NIH study classifies vision loss and retinal changes in Stargardt disease

National Eye Institute researchers developed and validated an artificial-intelligence-based method to evaluate patients with Stargardt, an eye disease that can lead to childhood vision loss. The… Source link

15 Fascinating Facts About the Eyes

Here are 15 fascinating facts about the eyes. Your eyes focus on 50 different objects every second. The only organ more complex than the eye is the brain. Your eyes can distinguish approximately 10 million different colors. It is impossible to sneeze with your eyes open. Ommatophobia is a fear of the eyes. 80 percent of all learning […]

Is ‘COVID Eye’ a Thing?

A 9-year-old boy was nearly blinded after developing “COVID eye.” He lost vision in one eye less than a week after testing positive for COVID-19. Physicians said the boy had developed orbital cellulitis. But… Source link

Study Finds Up to 30% of Patients with Wet Macular Degeneration Can Safely Stop Eye Injections

In a preliminary study of 106 people with “wet” age-related macular degeneration, Johns Hopkins Medicine researchers report that as many as a third of those with the blinding retinal disease may… Source link

Modular super-enhancer controls retinal development

Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Super-enhancers are clusters of enhancers that together regulate genes with important roles in cell… Source link

NIH researchers develop first stem cell model of albinism to study related eye conditions

Researchers at the National Eye Institute (NEI) have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA). The model’s… Source link

Could Eyedrops Replace Reading Glasses?

More than one-third of Americans have presbyopia, a gradual loss of near vision with age. Most people reach for eyeglasses or specialty contact lenses, but these are easily lost or can seem burdensome. Now, a… Source link

UC Irvine researchers reveal molecular mechanisms of eye disease using cryo-electron tomography

 Krzysztof Palczewski and his research team at the University of California Irvine revealed key structural determinants of rod photoreceptors–one of two major types of light-sensing cells in the… Source link

The First Alternative to a Monthly Injection for Wet AMD

There’s a new way to deliver sight-saving treatment for wet age-related macular degeneration (wet AMD) and it may make living with the chronic eye condition a lot easier. People with wet AMD need eye injections of a… Source link

Pathway to better eye health runs through the gut

Chronic noninfectious uveitis is a form of eye inflammation that, if left untreated, leads to vision loss and even blindness. Current treatments use broad anti-inflammatory medications such as… Source link

Happy Holidays from Belmont Eye Center

Link found between lupus, macular degeneration

Jayakrishna Ambati, M.D. Jayakrishna Ambati, University of Virginia, and colleagues reported that genetic material called short interspersed nuclear element RNAs (SINE RNAs) send immune factors… Source link

Cataract surgery does not cause disease progression in people with AMD

People with age-related macular degeneration (AMD) can undergo cataract surgery without fear of worsening their disease, according to the latest analysis of data from the Age-related Eye Disease… Source link

NIH researchers identify potential AMD drugs with stem-cell based research tool

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists…. Source link

Reimagining immunity in the eye

In a new study, the researchers show that immune cells respond to the lens, not just following an acute injury in the eye, but also to long-lasting inflammation. (Feed generated with FetchRSS) Source link

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Get Your Glow On holiday special at BEC Beauty! Treat yourself to a holiday glow and save 15% of your treatment for a limited time.

NIH study traces molecular link from gene to late-onset retinal degeneration

Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease. Researchers from… Source link

Study: Cataract surgery linked with lessened dementia risk

Cataracts affect most older adults at risk for dementia, and now researchers are finding strong evidence that cataract surgery is associated with a lower risk of developing dementia. Cecilia Lee,… Source link

A New Microscope for Imaging Neural Circuitry

Advancing our understanding of the human brain requires new insights into how neural circuitry works in mammals, including laboratory mice. These investigations require monitoring brain activity with… Source link

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